EVALUATION OF ANTIPEROXIDATIVE POTENTIAL OF WATER EXTRACT OF SPIRULINA PLATENSIS ON BUSULFAN-INDUCED LIPID PEROXIDATION USING 4-HYDROXY NONENAL AND NITRIC OXIDE AS MODEL MARKERS

Pharmaceutical Science-Pharmaceutical Chemistry

Authors

  • SUPRATIM RAY Division of Pharmaceutical Chemistry Dr. B C Roy College of Pharmacy & Allied Health Sciences, Bidhannagar, Durgapur, 713 206, India

Keywords:

Busulfan, Spirulina platensis, lipid peroxidation, 4-hydroxy-2-nonenal, nitric oxide

Abstract

This in vitro study was designed to evaluate free radical scavenging activity of water extract of Spirulina platensis on busulfan-induced lipid peroxidation using 4-hydroxy nonenal and nitric oxide as model markers. In this study goat liver has been used as liver source. The results suggest that busulfan could induce lipid peroxidation to a significant extent and it was also found that water extract of the Spirulina platensis has the ability to suppress the busulfan-induced toxicity.

Published

2011-12-30

How to Cite

RAY, S. (2011). EVALUATION OF ANTIPEROXIDATIVE POTENTIAL OF WATER EXTRACT OF SPIRULINA PLATENSIS ON BUSULFAN-INDUCED LIPID PEROXIDATION USING 4-HYDROXY NONENAL AND NITRIC OXIDE AS MODEL MARKERS: Pharmaceutical Science-Pharmaceutical Chemistry. International Journal of Life Science and Pharma Research, 1(1), L21-L27. Retrieved from https://www.ijlpr.com/index.php/journal/article/view/34

Issue

Volume 1 Issue 1, October - December 2011

Section

Research Articles

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