Evaluation of Efficacy and Safety of L-Methylfolate, Pyridoxal-5 Phosphate Andmecobalamin in Pregnancy: A Questionnaire-Based Study
Keywords:
Pregnancy, Vitamins, Folinext Gold, Nutritional deficiencyAbstract
Background: A balanced diet is essential during pregnancy to support healthy fetal development and prevent adverse outcomes. Due to increased nutritional demands, supplementation with key micronutrients like folic acid, pyridoxine, and mecobalamin is often necessary. Thus, this questionnaire-based study aimed to assess the efficacy and safety of these three supplements in pregnant women to improve pregnancy outcomes.
Methods: This questionnaire-based study was conducted among 51 physicians treating pregnant women prescribed the Folinext tablet, which contain L-methylfolate, pyridoxal-5 phosphate, and mecobalamin. A self-explanatory questionnaire comprising 17 closed-ended questions. The questionnaire focuses on last 10 pregnant women treated with Folinext tablet.
Results: A total of 51 physicians were included in the study. Out of the 51 physicians, more than half (56.86%) reported treating women with an obstetric history of inability to conceive. The majority of the physicians observed micronutrient deficiency, mainly folic acid, in 6/10 women. Thus, 78% of physicians prescribed the Folinext Gold tablet to all the women preconception and during pregnancy to improve fertility and avoid various complications like preeclampsia, gestational diabetes and pregnancy related hypertension. Also, all the physicians agreed to use a high dose of 5mg/day of folic acid as a supplement in women. More than 70% of the physicians rated the efficacy, safety and patient adherence to the treatment with this tablet as excellent.
Conclusion: This study demonstrated that the Folinext Gold tablet, containing L-methylfolate, pyridoxal-5 phosphate, and mecobalamin, is highly rated by physicians for its efficacy and safety in improving pregnancy outcomes.
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