Assessment of Prescribing Pattern and Factors Associated with Clinical Outcomes in Type-2 Diabetes Patients in A Tertiary Care Hospital
Pharmaceutical Science-Pharmacy practice
DOI:
https://doi.org/10.22376/ijpbs/lpr.2022.12.6.P170-%20179Keywords:
Type-2 Diabetes Mellitus, Prescribing Pattern, Metformin, Comorbidities, and ComplicationsAbstract
Our study is aimed to evaluate the prescribing pattern of antidiabetic drugs and factors associated with clinical outcomes in type-2 diabetes patients. The objectives of the study were to identify and evaluate the class of drugs, rationality, monotherapy or combination therapies prescribed, and demographic characteristics of the patients with the disease prospective observational study was conducted for 6 months in the General Medicine Department of KIMS Al Shifa Super Specialty Hospital, Perinthalmanna, Kerala. whichTotal113 subjectswere selected based on inclusion and exclusion criteria.Allrelevant patient datawere collected using a structured data collection form. Data were analyzed using the SPSS statistical software version 20 and MS Excel for descriptive statistics. Out of 113 patients studied, 55 (48.68%) were male and 58 (51.32%) were female. The majority of the patients were over the age of 65, with the fewest being under the age of 45. The mean age of the study population was found to be 59.64 years. The common comorbidity observed in the study population with Type-2 Diabetes Mellitus was hypertension (65%). 30 (26.54%) patients were found to have complications from diabetes mellitus. The average number of anti-diabetic drugs per prescription was 1.73. Thus, the study reveals that the presence of comorbidities and complications has a significant influence on glycaemic control. Elderly patients are at a higher risk of developing Type-2 diabetes mellitus. Metformin is the most commonly prescribed oral hypoglycemicagent, both in monotherapy and combination therapy. The prescribing trend appears to be moving towards combination therapy, particularly two drug therapies.
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Copyright (c) 2022 Balasubramanian T, Shabik Bin Rasheed, Shadia Badarudeen, Shahanas M.K, Shaheer K, Anandhi B, Abdul Rasheed A.R, Suhail P. T, Karthikeyan M
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