Insight on Nanoparticles, Green Synthesis and Applications in Drug Delivery System: A Comprehensive Review
Pharmaceutical Science- Pharmacy
DOI:
https://doi.org/10.22376/ijpbs/lpr.2022.12.5.P68-84Keywords:
Nanoparticles, Drug Delivery, Green Synthesis, Preparations, ApplicationAbstract
Nanoparticles and other new drug delivery methods like green synthesis are utilized as a physical strategy to change and improve the pharmacodynamic and pharmacokinetic aspects of various therapeutic compounds. Nanotechnology's fast advancement has opened the possibility of deploying designed nanoparticles that, interact with biological surroundings to cure illnesses. Interactions between cells and NPs, as well as the extracellular environment, may cause a cascade of biological consequences. Polymeric carbon nanotubes, NPs, liposomes, quantum dots, dendrimers, polymeric NPs, metallic NPs and green synthesis systems have all brought about recent alteration in drug delivery and the entire service of the medical system. Presently, distinct physical or chemical techniques have been utilized for NPs synthesis. However, most of those techniques are steeply-priced and probably risky for the organisms and environment. Therefore, there is necessity to expand a green and costpowerful approach of synthesis. Recently, the green synthesis processes are gaining a great attention. From their neighboring niche the microorganisms and plants have mounted the strength to accumulate and devour metal ions. It is confirmed that fungi yeast, bacteria, and plant cells can lessen inorganic metallic ions into metallic via means of their cellular metabolites. Both the stability and yield of biogenic NPs are quite acceptable. This review provides an overview of NPs, including their kinds, highlighted green synthesis, benefits, and drawbacks, features of NPs, NPs preparation methods, and the most relevant uses. It is notably predicted that biogenic NPs might be viable and affordable options for medicating drug resistant infections in near future.
References
Anna PG. Nanotechnology and its applications in medicine. J Chem. 2015;5(2):81-9. Doi:10.4172/2161-0444.1000247.
Ingle AP, Shende S, Pandit R, Paralikar P, Tikar S, Kon K, Rai M. Nanotechnological applications for the control of pulmonary infections. The Microbiology of Respiratory System Infections. 2016:223–35. doi: 10.1016/B978-0-12-804543-5.00015-4.
Khan I,Saeed K, Khan I. Nanoparticles: properties, applications and toxicities. Arab J Chem. 2019;12(7):908-31. doi: 10.1016/j.arabjc.2017.05.011.
Martins P, Fernandess RA, Baptista VP. Nanoparticle drug delivery systems: recent patents and applications in nanomedicine. Bentham Sci Publish J.2013;3(2):1877-9123. http://dx.doi.org/10.2174/1877912304666140304000133
Hasan S. A Review on nanoparticles: their synthesis and types biosynthesis: mechanism. 2015;4:9-11.
Tai CY, Tai C, Chang M, Liu H. Synthesis of magnesium hydroxide and oxide nanoparticles using a spinning disk reactor. IndEngChem Res. 2007;46(17):5536-41. doi: 10.1021/ie060869b.
Jong De HW, Paul B. Drug delivery and nanoparticles: applications and hazards. Int J Nanomedicine.2008;3(2):133-49. doi: 10.2147/IJN.S596.
Kumar PR, Sagadevan S, Savitha S. Beneficial applications of nanoparticles in medical field-a review. Int J Pharmatechnol Res.2014;6(5):1711-7.
Bhatia S. Natural polymer drug delivery systems. Springer Int Publish Switzerland. 2016.
Barhoum A. History and development of nanoparticles and nanostructured materials. ChemSci J.2016;7(3):1-14.http://dx.doi.org/10.4172/2150-3494.C1.006
Heera P, Shanmugam S. Nanoparticle characterization and application: an overview. Int J CurrMicrobiolAppl Sci. 2015;4(8):379-86.
Asha Spandana KM, Bhaskaran M, Karri VVSNR, Natarajan J. A comprehensive review of nano drug delivery system in the treatment of CNS disorders. J Drug DelivSci Technol.2020;57. doi: 10.1016/j.jddst.2020.101628, PMID 101628.
Bahadar H, Maqbool F, Niaz K, Abdollahi M. Toxicity of Nanoparticles and an Overview of Current Experimental Models. Iran Biomed J. 2016;20(1):1-11. doi: 10.7508/ibj.2016.01.001.
Singh A, Gautam PK, Verma A. Green synthesis of metallic nanoparticles as effective alternatives to treat antibiotics resistant bacterial infections: A review Biotechnol Rep (Amst). 2021;19;29:e00578. doi:10.1016/j.btre.2020.e00427.
Oxana VK, Boris IK, Cesar MO, Yolanda PM, Israel L. Green synthesis of chemical compound and materials. Royal Soc Open Sci. 2019;6(11):1-41.https://doi.org/10.1098/rsos.191378.
Kalpana VN, Rajeshwari VD. A review on green synthesis, biomedical application, and toxicity study of ZnO NPs. Bioinorganic Chem Appli.2018:1-12.https://doi.org/10.1155/2018/3569758.
Shandilya N,Olivier LB, Martin M. A review on the study of the generation of (Nano) particles Aerosols during the Mechanical Solicitation of Materials. J Nanomat. 2014. https://doi.org/10.1155/2014/289108
Andrew JC, Devin TW, Johnathan EZ, Mark ED. CRLX101 nanoparticles localize in human tumors and not in adjacent, non-neoplastic tissue after intravenous dosing. PNAS. 2016;113 (14):3850-3854. https://doi.org/10.1073/pnas.1603018113
Munir H, Bilal M, Mulla SI, Khan AH, Iqbal HMN. Plant-Mediated green synthesis of nanoparticles. Adv in Sci, Technol&Innov. 2021;75-89. doi:10.1007/978-3-030-67884-5_4.
Rosenholm JM, Eriksson JE, Peuhu E, Sahlgren C, Lindén M. Targeted intracellular delivery of hydrophobic agents using mesoporous hybrid silica nanoparticles as carrier systems. Nano Letters. 2009;9(9):3308-3311. https://doi.org/10.1021/nl901589y
Laura C, Subhani B, Marshall J, Tony G, Tony G, Godson O, Aruna W, Peter A, Selamawit W. Foodborne Patho and Dis. 2020.504-511. http://doi.org/10.1089/fpd.2019.2714
Benelli G. Green Synthesis of Nanomaterials. Nanomaterials (Basel). 2019;9(9):1275. doi:10.3390/nano9091275.
Dada OA, Ojediran OJ, Dada FE, Olalekan AP, Awakan OJ. Green synthesis and characterization of silver nanoparticles using CalotropisProcera extract. J ApplChemSci Int. 2017 8(4): 137-143.
Dizaj SM, VazifehaslZh,Salatin S, Adibkia KH, Javadzadeh Y. Nanosi-zing of drugs: effect on dissolution rate. Res Pharm Sci.2015;10(2):95-108. PMID 26487886.
Gwinn MR, Vallyathan V. Nanoparticles: health effects--pros and cons. Environ Health Perspect.2006;114(12):1818-25. doi: 10.1289/ehp.8871, PMID 17185269.
Bayda S, Adeel M, Tuccinardi T, Cordani M, Rizzolio F. The history of nanoscience and nanotechnology: from chemical-physical applications to nanomedicine. Molecules. 2019;25(1):112. doi: 10.3390/molecules25010112, PMID 31892180.
Jeevanandam J, Barhoum A, Chan YS, Dufresne A, Danquah MK. Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations. Beilstein J Nanotechnol.2018;9:1050-74. doi: 10.3762/bjnano.9.98, PMID 29719757.
Cooper DL, Conder CM. Nanoparticles in drug delivery: mechanism of action, formulation and clinical application towards reduction in drug-associated nephrotoxicity. Expert Opinion Drug Deliv J. 2014;11(10):1744-7593.http://dx.doi.org/10.1517/17425247.2014.938046.
RocoMC. The long view of nanotechnology development: the National Nanotechnology Initiative at 10 years. J NanopartRes.2011;13(2):427-45. doi: 10.1007/s11051-010-0192-z.
Tiruwa R. A review on nanoparticles- preparation and evaluation parameters. Indian J Pharm Bio Res.2015;4(2):27-31. doi: 10.30750/ijpbr.4.2.4.
Simko M, Fiedeler U, Nentwich M, Gazso A. Production of nanoparticles and nanomaterials. Nano Trust Dossier.2011.
Rajput N. Method of preparation of nanoparticles- a review. Int J AdvEng Technol.2015;7(4):1806-11.
Murthy SK. Nanoparticles in modern medicine: state of the art and future challenges. Int J Nanomedicine. 2007;2(2):129-41. PMID 17722542.
Naik J. Nano based drug delivery. International Association of Physical Chemists;2015.
Witharana C, Wanigasekara J. Applications of nanotechnology in drug delivery and design - aninsight. CurrTrenBiotechnol Pharm.2016;10(1):78-91.
Subbenaik SC, Kole C. Physical and chemical nature of nanoparticles. Springer Int Publish Switzerland. 2016.
Dizaj SM, JafariS, KhosroushahiAY. A sight on the current nanoparticle-based gene delivery vectors. Nanoscale Res Lett. 2014;9(1):252. doi: 10.1186/1556-276X-9-252, PMID 24936161.
Mody VV, Siwale R, Singh A, Mody HR. Introduction to metallic nanoparticles. J Pharm Bioallied Sci.2010;2(4):282-9. doi: 10.4103/0975-7406.72127, PMID 21180459.
Gatoo AM, Naseem S, ArfatMY, Dar MA, Qasim K, Zubair S. Physicochemical properties of nanomaterials: implication in associated toxicmanifestations. J biomedicalres. 2014.
Christian P, Von der Kammer F, Baalousha M, Hofmann T. Nanoparticles: structure, properties, preparation and behaviour in environmental media. Ecotoxicology.2008;17(5):326-43. doi: 10.1007/s10646-008-0213-1, PMID 18459043.
Soares S, Sousa J, Pais A, Vitorino C. Nanomedicine: principles, properties and regulatory issues. Front Chem.2018;6:360. doi: 10.3389/fchem.2018.00360, PMID 30177965.
Nikam AP, Ratnaparkhiand MP, Chaudhari SP. Nanoparticles – an overview. Int J Res Dev Pharm Life Sci.2014;3(5):1121-7.
Medina C, Santos-Martinez MJ, Radomski A, Corrigan OI, Radomski MW. Nanoparticles: pharmacological and toxicological significance. Br J Pharmacol.2007;150(5):552-8. doi: 10.1038/sj.bjp.0707130, PMID 17245366.
Goud R, Jones R, Banerjee S, Robertson G. Useof nanotechnology to develop multi drug inhibitors for cancer therapy. J Nanomed Nano. 2014;4(6):1-31.http://dx.doi.org/10.4172/2157-7439.1000184
Singh S, Pandy VK, Tewari RP, Agarwal V. Nanoparticle based drug delivery system: advantages and applications. Indian J Sci Technol. 2011;4(3):0974- 6846.
Kumar P, Kulkarni PK.Anjali and Srivastava A. JChem PharmRes.2015;7(8):703-12.
Mukherjee B, Dey NS, Maji R, Bhowmik P, Das PJ, Paul P. Current Status and Future Scope for Nanomaterials in drug delivery. Intech Open journal.doi: 10.5772/58450.
Midha K, Diwan P, Mampi D. A recent update on nanoparticles. Advanced research in pharmaceutical and biological an international peer reviewed. J Pharmal Allied Res.2018;8(1):2250-0774.
Bose S. Nano drug delivery System in pharmacy and chemistry. J Pharm Biolol Sci.2015;10(5):01-6. doi: 10.9790/3008-10520106.
Salata OV. Applications of nanoparticles in biology and medicine. J Nanobiotechnology. 2004;2(1):3. doi: 10.1186/1477-3155-2-3, PMID 15119954.
Nasimi P, Haidari M. Medical use of nanoparticles: drugdelivery and diagnosisdiseases. IntJGreen Nanotechnol.2013;1:1-6. doi: 10.1177/1943089213506978.
Kaur P, Kaur L, Khan MU. Nanoparticles as novel drug delivery system. Int J Res Pharm Chem.2012;2(3):2231-781.
Shah M, Badwaik VD, Kherde Y, WaghwaniHK, Modi T, Aguilar ZP, Rodgers H, Hamilton W, Marutharaj T, Webb C, Lawrenz MB, Dakshinamurthy R. Gold nanoparticles: various methods of synthesis and antibacterial applications. Front Biosci (Landmark Ed). 2014;19:1320-44. doi: 10.2741/4284, PMID 24896353.
Gressler S, Fiedeler U, Gazso A, Nentwich M. Nanotechnology in cosmetics. J Nano Trust Dossier. 2010.
Ekambaram P, Zarekar NS Shengde RS. Solid lipid nanoparticles. Nano SciNanotechnol Res. 2017;4(2):67-72.Doi- 10.12691/nnr-4-2-5.
Rizvi SAA, Saleh AM. Applications of nanoparticle systems in drug delivery technology. Saudi PharmJ.2018;26(1):64-70. doi: 10.1016/j.jsps.2017.10.012, PMID 29379334.
S Anu Mary Ealia and MPSaravanakumar. A review on the classification, characterization and synthesis of nanoparticle and their application. IOP ConfSer Mater Sci Eng.2017;263. PMID 032019.
Rana A, Yadav K, Jagadevan S, A comprehensive review on green synthesis
of nature-inspired metal nanoparticles: Mechanism, application and toxicity, J of Cleaner. https://doi.org/10.1016/j.jclepro.2020.122880
Vanlaveni C, Lallianrawna S, Biswas A, Selvaraj M, Changmai B, Rokhum LS. Green synthesis of silver nanoparticle using plant extract and their antimicrobial activity: a review of recent literature. RSV Adv.2021. PMID 112804.
Mohanraj VJ, Chen Y. Nanoparticles-a review. Trop J Pharm Res. 2006;5(1):561-73. doi: 10.4314/tjpr.v5i1.14634.
Zhang D, Ma XL, Gu Y, Huang H, Zhang G. Green synthesis of metallic nanoparticle and their potential application to treat cancer. Forntier Chem. 2020;8:799.https://dx.doi.org/10.3389%2Ffchem.2020.00799.
Ahmad S, Munir S, Zeb N, Ullah A, Khan B, Ali J, Bilal M, Omer M, Alamzeb M, Salman SM, Ali S. Green nanotechnology a review on green synthesis of nanoparticles. Int J Nanomedicine.2019;14:5087-107. doi: 10.2147/IJN.S200254, PMID 31371949.
Rauwel P, Kuunal S, Ferdov S, Rauwel E. A review on green synthesis of silver nanoparticle and their morphological studies via TEM.Adv Mat Sci Tech;2015. p. 1-9.https://doi.org/10.1155/2015/682749.
Izaj I, Gilani E, Nazir A, Bukhari A. Detailed review on chemical, physical, green synthesis, classification, characterization and application of nanoparticles. Green Chem Lett Rev.2020;13(3):59-81.https://doi.org/10.1080/17518253.2020.1802517.
Jadoun S, Arif R, Jangid NK, Meena RK. Green synthesis of nanoparticles using plant extract –a review. Environ Chem Lett.2021;19(1):355-74. doi: 10.1007/s10311-020-01074-x.
Singh J, Dutta T, Kim KH, Rawat M, Samdda P, Kumar P. Green synthesis of metals and their oxide nanoparticles application for environmental remediation. J Nanotechnol.2018;16:84.https://doi.org/10.1186/s12951-018-0408-4
Castillo-Henríquez L, Alfaro-Aguilar K, Ugalde-Álvarez J, Vega-Fernández L, Montes de Oca-Vásquez G, Vega-Baudrit JR. Green synthesis of gold and silvernanoparticles from plantextracts and theirpossibleapplications as antimicrobialagents in the agriculturalarea. Nanomaterials (Basel). 2020;10(9):1763. doi: 10.3390/nano10091763, PMID 32906575.
Okafor F, Janen A, Kukhtareva T, Edwards V, Curley M. Green synthesis of silver nanoparticles, their characterization, application and antibacterial activity. Int J Environ Res Public Health. 2013;10(10):5221-38. doi: 10.3390/ijerph10105221, PMID 24157517.
Ahmad S, Munir S, Zeb N, Ullah A, Khan B, Ali J, Bilal M, Omer M, Alamzeb M, Salman SM, Ali S. Green nanotechnology: a review on green synthesis of silver nanoparticles - an ecofriendly approach. Int J Nanomedicine. 2019;14:5087-107. doi: 10.2147/IJN.S200254, PMID 31371949.
Zhang D, Ma XL, Gu Y, Huang H, Zhang GW. Green synthesis of metallicnanoparticles and theirpotentialapplications to treatcancer. Front Chem.2020;8:799. doi: 10.3389/fchem.2020.00799, PMID 33195027.
Fahmy SA, Preis E, Bakowsky U, Azzazy HME. Platinum nanoparticles: greensynthesis and biomedicalapplications. Molecules. 2020;25(21):4981. doi: 10.3390/molecules25214981, PMID 33126464.
Erci F, Cakir-Koc R, Isildak I. Green synthesis of silver nanoparticles using Thymbraspicata L. var. spicata (zahter) aqueous leaf extract and evaluation of their morphology-dependent antibacterial and cytotoxic activity. Artif Cells NanomedBiotechnol. 2018;46(sup1):150-158. doi: 10.1080/21691401.2017.1415917.
Lee SH, Jun BH. Silver Nanoparticles: Synthesis and Application for Nanomedicine. Int J Mol Sci. 2019;20(4):865. doi:10.3390/ijms20040865.
Letchumanan D, Sok SPM, Ibrahim S, Nagoor NH, Arshad NM. Plant-based biosynthesis of copper/copper oxide nanoparticles: an update on their applications in biomedicine, mechanisms, and toxicity. Biomolecules. 2021;11(4):564.
Rabiee N, Bagherzadeh M, Kiani M. Biosynthesis of copper oxide nanoparticles with potential biomedical applications. Int J Nanomedicine. 2020;15:3983-3999. doi:10.2147/IJN.S255398.
Ziental D, Czarczynska-Goslinska B, Mlynarczyk DT, Glowacka-Sobotta A, Stanisz B, Goslinski T, Sobotta L. Titanium dioxide nanoparticles: prospects and applications in medicine.Nanomaterials(Basel,Switzerland).10(2),387.https://doi.org/10.3390/nano10020387.
Shah M, Fawcett D, Sharma S, Tripathy SK, Poinern GEJ. Green synthesis of metallicnanoparticles via biologicalentities. Materials (Basel). 2015;8(11):7278-308. doi: 10.3390/ma8115377, PMID 28793638.
Castillo-Henríquez L, Alfaro-Aguilar K, Ugalde-Álvarez J, Vega-Fernández L, Montes de Oca-Vásquez G, Vega-Baudrit JR. Green synthesis of gold and silvernanoparticles from plantextracts and theirpossibleapplications as antimicrobialagents in the agriculturalarea. Nanomaterials (Basel). 2020;10(9):1763. doi: 10.3390/nano10091763, PMID 32906575.
Rana A, Yadav K, Jagadevan S. A comprehensive review on green synthesis of nature-inspired metal nanoparticles: mechanism, application and toxicity.Journal of Cleaner Production. 2020;122880–. doi:10.1016/j.jclepro.2020.122880
Nath D, Banerjee P. Green nanotechnology-a new hope for medical biology. Environ ToxicolPharmacol. 2013;36:997-1014.http://dx.doi.org/10.1016/j.etap.2013.09.002.
Ovais M, Khalil AT, Ayaz M, Ahmad I, Nethi SK, Mukherjee S. Biosynthesis of metal nanoparticles via microbial enzymes: a mechanistic approach. Int J Mol Sci. 2018;19(12):4100. doi:10.3390/ijms19124100.
Aboyewa JA, Sibuyi NRS, Meyer M, Oguntibeju OO. Green synthesis of metallic nanoparticles using some selected medicinal plants from Southern Africa and their biological applications. Plants (Basel). 2021;10(9):1929. doi:10.3390/plants10091929.
Shah M, Fawcett D, Sharma S, Tripathy SK, Poinern GEJ. Green synthesis of metallic nanoparticles via biological entities. Materials (Basel). 2015;8(11):7278-7308. doi:10.3390/ma8115377
Rajashekar K, Nandita D, Sudip D. Nanoparticulate systems for therapeutic and diagnostic applications. EmerNanotechnolosDiagn Drug Delivand Med Devi. 2017:105-44.
Bhardwaj B, Singh P, Kumar A, Kumar S, Budhwar V. Eco-friendly greener synthesis of nanoparticles. Adv Pharm Bull. 2020;10(4):566-576. doi:10.34172/apb.2020.067.
Kumari B. A review on nanoparticle: their preparation method and classification. Ind Res J Pharm Sci. 2018;5(2).
Merlin JJ, Rajan SS. A review on synthesis and preparation of nanoparticles. J Cancer Sci Treat. 2020;2(1):87-9.
Nagavarma BVN, Hemant KS, Yadav Ayuz A, Vasudha LS, Shivakumar HG. Different techniques for preparation of polymeric nanoparticles - a review. Asian J Pharm Clin Res. 2012;5:1-8.
Joachim A. Synthesis of organic and bioorganic nanoparticles: an overview of the preparation methods. London: Springer-Verlag;2013. p. 27-30.
Mourdikoudis S, Pallares RM , Thanh NTK . Characterization techniques for nanoparticles: comparison and complementarity upon studying nanoparticle properties. Nanoscale. 2018;13;10(27):12871-12934. doi: 10.1039/c8nr02278j.
Shnoudeh A, Hamad I, Abdo RW, Qadumii L, Jaber AY, Surchi HS, Alkelany SZ. Synthesis, characterization, and applications of metal nanoparticles. Biomat Bionanotechno.2019;528-585. https://doi.org/10.1016/B978-0-12-814427-5.00015-9
Sovan LP, Utpal J, Manna PK, Mohanta GP, Manavalan R. Nanoparticle: an overview of preparation and characterization.JAppl Pharm Sci.2011;1(6):228-34.
Tyagi PK, Quispe C, Herrera-Bravo J, Tyagi S, Mrunal B, Kumar M. Synthesis of Silver and Gold Nanoparticles: Chemical and Green Synthesis Method and Its Toxicity Evaluation against Pathogenic Bacteria Using the ToxTrak Test. 2021;1-12. https://doi.org/10.1155/2021/3773943
Katmis A, Fide S, Karaismailoglu S, Derman S. Synthesis and characterization method of polymeric nanoparticle. CharaApplNnano. 2018;1:1-9. doi:10.24294/can.v1i2.791.
Kaur LS, Sandeep K, Punam G. An overview, preparation, characterization and application of nanoparticles. J Drug DelivTher. 2020;10(6-s):159-67.
Guo S, Fu D, Utupova A, Sun D, Zhou M, Jin Z, Zhao K. Application of polymer based nanoparticle in vaccine field. Nanotechnol Rev. 2019;8:143-155. https://doi.org/10.1515/ntrev-2019-0014
Pal S, Jana U, Manna PK, Mohanta GP, Manavalan R. Nanoparticle: an overview of preparation and characterization. J Appl Pharm Sci.2011;1(6):228-34.
Jeevanandam J, Barhoum A, Chan YS, Dufresne A, Danquah MK. Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations. Beilstein J Nanotechnol.2018;9(9):1050-74. doi: 10.3762/bjnano.9.98, PMID 29719757.
Beena K. A review on nanoparticles: their preparation method and applications. Ind Res J PharmSci. 2018;5(2):1420-6.
Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R. Engineering precision nanoparticles for drug delivery. Nat Rev Drug Discov. 2021;20(2):101-24. doi: 10.1038/s41573-020-0090-8, PMID 33277608.
Baig N, KammakakamI.FalathW.Nanomaterials: a review of synthesis methods, properties, recent progress, and challenges. MaternAdvan. 2021;2:1821.https://doi.org/10.1039/D0MA00807A.
Xiaopei H, Yuting Z, Tingting D, Jiang L, Hang Z. Multifunctional gold nanoparticles: A novel nano material for various medical applications and biological activities. Front Bioeng Biotechnol.2020.https://doi.org/10.3389/fbioe.2020.00990
Dawadi S, Katuwal S, Gupta A, Lamichhane U, Thapa R, Jaisi S, Lamichhane G, Bhattarai DP, Parajuli N. Current research on silver nanoparticles: synthesis, characterization, and applications. Journal of Nanomaterials. 2021;2021:1-23. doi: 10.1155/2021/6687290.
SimS, WongNK. Nanotechnology and its use in imaging and drug delivery (Review). BiomedRep. 2021;14(5):42. doi: 10.3892/br.2021.1418, PMID 33728048.
Krishna RN, Gyathri R, Priya V. Nanoparticles and their applications- a review. J Pharm Sci Res.2017;9(1):24-7.
Antonio JR, Antônio CR, Cardeal IL, Ballavenuto JM, Oliveira JR. Nanotechnology in dermatology. An Bras Dermatol.2014;89(1):126-36. doi: 10.1590/abd1806-4841.20142228, PMID 24626657.
DeLouise LA. Applications of nanotechnology in dermatology. J Invest Dermatol vol. 132.2012;2(3 Pt 2):964-75. doi: 10.1038/jid.2011.425, PMID 22217738.
Sharma A, Harikumar SL. Qualiy by design approach for development and optimization of nitrendipine loaded niosomal gel for accentuated transdermal delivery. Int J Appl Pharm.2020;12(5):181-9.https://doi.org/10.22159/ijap.2020v12i5.38639
Sharma A, Singh AP, Harikumar SL. Development and optimization of nanoemulsion based gel for enhanced transdermal delivery of nitrendipine using box-behnken statistical design. Drug DevIndPharm.2020;46(2):329-42. doi: 10.1080/03639045.2020.1721527, PMID 31976777.
Jin C, Wang K, Oppong-Gyebi A, Hu J. Application of nanotechnology in cancerdiagnosis and therapy - Amini-review. Int J Med Sci.2020;17(18):2964-73. doi: 10.7150/ijms.49801, PMID 33173417.
Yao Y, Zhou Y, Liu L, Xu Y, Chen Q, Wang Y, Wu S, Deng Y, Zhang J, Shao A. Nanoparticle-Based drug delivery in cancer therapy and its role in overcoming drug resistance. Front Mol Biosci.2020;7:193. doi: 10.3389/fmolb.2020.00193, PMID 32974385.
Mullaicharam AR. Nanoparticles in drug delivery system. Int J NutrPharmacolNeurol Dis.2011;1(2):103-21. doi: 10.4103/2231-0738.84194.
YuZ, GaoL, ChenK, Zhang W, Zhang Q, Li Q, Hu K. Nanoparticles: A new approach to upgrade cancer diagnosis and treatment. NanoscaleRes Lett.2021;16(1):88. doi: 10.1186/s11671-021-03489-z, PMID 34014432.
Herranz F, Almarza E, Rodríguez I, Salinas B, Rosell Y, Desco M, Bulte JW, Ruiz-Cabello J. The application of nanoparticles in gene therapy and magnetic resonance imaging. Microsc Res Tech.2011Jul;74(7):577-91. doi: 10.1002/jemt.20992, PMID 21484943.
Tomoda K, Makino K. Nanoparticles for transdermal drug delivery system (TDDS). Colloid Interface Sci Pharm Res Develop. 2014:131-47.
KafshdoozT, KafshdoozL, AkbarzadehA, HanifehpourY, JooSW. Applications of nanoparticle systems in gene delivery and gene therapy. ArtifCellsNanomedBiotechnol. 2016;44(2):581-7. doi: 10.3109/21691401.2014.971805, PMID 25365242.
KelesE,SongY,DuD,DongW-J, LinYuehe. Recent progress in nanomaterials for gene delivery applications.Biomater Sci.2016;4(9):1291-309. doi: 10.1039/c6bm00441e, PMID 27480033.
Hashim PW, Nia JK, Han G, Ratner D.Nnaoparticle in dermatology surgery. J AcadDermatol. 2020;83(4):1144-9.https://doi.org/10.1016/j.jaad.2019.04.020
Fan C, Joshi J, Li F, Xu B, Khan M, Yang J, Zhu W. Nanoparticle-mediated drug delivery for treatment of ischemic heart disease. FrontBioengBiotechnol. 2020;8:687. doi: 10.3389/fbioe.2020.00687, PMID 32671049.
Pala R, Anju VT, Dyavaiah M, Busi S, Nauli SM. Nanoparticle-mediated drug delivery for the treatment of cardiovascular diseases. Int J Nanomedicine. 2020;15:3741-69. doi: 10.2147/IJN.S250872, PMID 32547026.
DiSanto RM, Subramanian V, GuZ. Recent advances in nanotechnology for diabetes treatment. Wiley Inter discip Rev NanomedNanobiotechnology. 2015;7(4):548-64. doi: 10.1002/wnan.1329, PMID 25641955.
He Y, Al-Mureish A, Wu N. Nanotechnology in the treatment of diabetes complications: a comprehensive review. J Diabetes Res.2021:1-11.https://doi.org/10.1155/2021/6612063.
Guerrero Correa M, Martínez FB, Vidal CP, Streitt C, Escrig J, de Dicastillo CL. Antimicrobial metal-based nanoparticles: a review on their synthesis, types and antimicrobial action. Beilstein J Nanotechnol.2020;11:1450-69. doi: 10.3762/bjnano.11.129, PMID 33029474.
Sharmin S, Rahaman MM, Sarkar C, Atolani O, Islam MT, Stephen O. Nanoparticles as antimicrobial and antiviral agents: A literature-based perspective study. Heliyon. 2021, 2021:7(3).https://dx.doi.org/10.1016%2Fj.heliyon.2021.e06456
Omerović N, Vranić E. Application of nanoparticles in ocular drug delivery systems. Health Technol. 2020;10(1):61-78. doi: 10.1007/s12553-019-00381-w.
Zhou HY, Hao JL, Wang S, Zheng Y, Zhang WS. Nanoparticles in the ocular drug delivery. Int J Ophthalmol.2013;6(3):390-6. doi: 10.3980/j.issn.2222-3959.2013.03.25, PMID 23826539.
Karthikeyan RD, Amaldas J. Green synthesis and characterization of silver nanoparticle (agnps) using Artemisia annua I. and its antibacterial, antifungal activity. Int J Pharma Bio Sci. 2018;9(4):111-121. DOI:http://dx.doi.org/10.22376/ijpbs.2018.9.4.p111-121.
Thakur S, Mohan GK. Green synthesis of silver nanoparticles of boswellic acid and its in-vitro anticancer activity. Int J Pharma Bio Sci. 2019;10(3):92-100.http://dx.doi.org/10.22376/ijpbs.2019.10.3.p92-100
Published
How to Cite
Issue
Section
Copyright (c) 2022 Abhishek Sharma, Ram Babu Sharma, Ashima Verma, Rakesh Thakur
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
