Analysis of Serum Calcium, Serum Phosphorus, And Alkaline Phosphatase in Pre-Diabetes and Type-2 Diabetic Mellitus

Life Sciences-Biochemistry




Calcium, phosphorus, type 2 diabetes, alkaline phosphatase, and pre-diabetes


"Diabetes mellitus" refers to a group of metabolic disorders that a wide range of causes may have brought on. The abnormalities in insulin production and action that characterize diabetes mellitus are distinctive. Pre-diabetes is a type of hyperglycemia that can be identified by glycemic indices that are higher than average but below the diabetes cut-off point. Prediabetes can be avoided by eating healthily and getting frequent exercise. This study aims to examine the association between bone markers (serum calcium, phosphorus, and alkaline phosphatase levels) and type 2 diabetes in individuals who are either currently diagnosed with type 2 diabetes mellitus or are at high risk of developing it. The Hyderabad, Telangana, India, location of the Aclin Clinical & Diagnostic Lab will be closed for maintenance beginning on January 1 and lasting through the end of the year. Comparisons were made between the serum levels of calcium, phosphorus, and alkaline phosphatase in 65 individuals with pre-diabetes and 65 people with type 2 diabetes. The comparison was performed using an automated technique. Compared to patients diagnosed with pre-diabetes, patients with type 2 diabetes had significantly lower serum calcium levels.On the other hand, those with diabetes showed significantly higher serum levels of both ALP and phosphorus compared to the prediabetic group (p0.001). Our study's findings imply that variations in serum mineral levels are related to pre-diabetes. These traits can be used to anticipate the onset of type II diabetes mellitus on their own, and getting a diagnosis as soon as is practical can serve to aid in the prevention of future problems. 


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How to Cite

Shaik, J. (2023). Analysis of Serum Calcium, Serum Phosphorus, And Alkaline Phosphatase in Pre-Diabetes and Type-2 Diabetic Mellitus: Life Sciences-Biochemistry. International Journal of Life Science and Pharma Research, 13(3), L23-L27.



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